Koichi Goto Selected Research

Dimyristoylphosphatidylcholine (DMPC)

6/2013	Hybrid liposomes inhibit tumor growth and lung metastasis of murine osteosarcoma cells.
7/2011	Selective accumulation of hybrid liposomes into adult T-cell leukemia cells along with induction of apoptosis.
1/2011	Therapeutic effects of hybrid liposomes composed of phosphatidylcholine and docosahexaenoic acid on the hepatic metastasis of colon carcinoma along with apoptosis in vivo.
1/2011	Remarkable inhibitory effects of hybrid liposomes on growth of human colon cancer cells through induction of cell cycle arrest along with apoptosis.
1/2011	[Experimental therapeutic effects of hybrid liposomes on the Alzheimer's disease in vitro].
7/2008	Remarkably high inhibitory effects of docosahexaenoic acid incorporated into hybrid liposomes on the growth of tumor cells along with apoptosis.
3/2008	Induction of apoptosis of human tumor cells by hybrid liposomes including docosahexaenoic acid.
9/2004	Inhibitory effects of extracts from peels of Citrus natsudaidai encapsulated in hybrid liposomes on the growth of tumor cells in vitro.
4/2002	Remarkably enhanced inhibitory effects of three-component hybrid liposomes including sugar surfactants on the growth of lung carcinoma cells.

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Koichi Goto Research Topics

Disease

100	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2022 - 02/2002
91	Neoplasms (Cancer) 05/2022 - 01/2002
31	Lung Neoplasms (Lung Cancer) 04/2022 - 02/2004
22	Adenocarcinoma of Lung 12/2021 - 04/2002
19	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 03/2021 - 12/2006
9	Adenocarcinoma 04/2021 - 11/2004
9	Disease Progression 01/2021 - 01/2013
9	Carcinoma (Carcinomatosis) 11/2019 - 04/2002
9	Neoplasm Metastasis (Metastasis) 06/2017 - 03/2006
7	Neutropenia 01/2020 - 07/2004
6	Febrile Neutropenia 01/2020 - 10/2015
6	Interstitial Lung Diseases (Interstitial Lung Disease) 07/2015 - 09/2010
5	Diarrhea 06/2022 - 12/2010
5	Hypertension (High Blood Pressure) 01/2022 - 05/2010
4	Exanthema (Rash) 01/2022 - 09/2013
4	Nausea 10/2020 - 12/2015
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2017 - 06/2012
4	Thymoma (Thymic Carcinoma) 07/2015 - 09/2003
3	Thrombocytopenia (Thrombopenia) 01/2022 - 12/2015
3	Necrosis 01/2021 - 07/2019
3	Vomiting 10/2020 - 01/2018
3	Anorexia 01/2020 - 01/2016
3	Radiation Pneumonitis 01/2020 - 06/2008
3	Colonic Neoplasms (Colon Cancer) 12/2019 - 01/2011
3	Brain Neoplasms (Brain Tumor) 11/2018 - 03/2006
3	Breast Neoplasms (Breast Cancer) 07/2009 - 03/2004
2	Fever (Fevers) 01/2022 - 02/2004
2	Hyponatremia 01/2021 - 01/2020
2	Respiratory Insufficiency (Respiratory Failure) 01/2021 - 09/2010
2	Colorectal Neoplasms (Colorectal Cancer) 10/2020 - 05/2016
2	Hemorrhage 05/2020 - 01/2018

Drug/Important Bio-Agent (IBA)

27	Tyrosine Kinase InhibitorsIBA 12/2021 - 12/2008
26	ErbB Receptors (EGF Receptor)IBA 01/2022 - 01/2006
24	Cisplatin (Platino)FDA LinkGeneric 03/2021 - 02/2002
17	PlatinumIBA 04/2022 - 07/2003
13	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2022 - 09/2013
12	Liposomes (Liposome)IBA 06/2013 - 04/2002
11	Docetaxel (Taxotere)FDA Link 09/2019 - 02/2002
11	Gefitinib (Iressa)FDA Link 10/2018 - 11/2004
9	Bevacizumab (Avastin)FDA Link 01/2022 - 10/2010
9	Carboplatin (JM8)FDA LinkGeneric 03/2021 - 10/2007
9	Vinorelbine (Navelbine)FDA LinkGeneric 01/2021 - 04/2004
9	Dimyristoylphosphatidylcholine (DMPC)IBA 06/2013 - 04/2002
8	Pemetrexed (MTA)FDA Link 04/2021 - 12/2015
8	NivolumabIBA 01/2021 - 01/2016
7	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2016
7	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 12/2008
7	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2004
7	CrizotinibIBA 10/2020 - 01/2017
7	Pharmaceutical PreparationsIBA 05/2020 - 01/2002
7	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 06/2013 - 09/2004
6	osimertinibIBA 12/2021 - 11/2019
6	vandetanib (ZD6474)IBA 01/2021 - 07/2013
6	Biomarkers (Surrogate Marker)IBA 01/2021 - 12/2013
6	Irinotecan (Camptosar)FDA LinkGeneric 08/2016 - 01/2002
6	Therapeutic UsesIBA 02/2015 - 01/2011
5	AfatinibIBA 01/2021 - 09/2013
5	Cadherins (E-Cadherin)IBA 01/2021 - 06/2012
5	alectinibIBA 01/2021 - 01/2017
4	selpercatinibIBA 06/2022 - 01/2020
4	Aspartate Aminotransferases (Aspartate Transaminase)IBA 06/2022 - 10/2018
4	Alanine Transaminase (SGPT)IBA 06/2022 - 10/2018
4	Phosphotransferases (Kinase)IBA 01/2022 - 12/2015
4	pembrolizumabIBA 04/2021 - 01/2021
4	Paclitaxel (Taxol)FDA LinkGeneric 10/2020 - 10/2007
4	Biological ProductsIBA 01/2020 - 03/2012
3	entrectinibIBA 05/2022 - 01/2020
3	Formaldehyde (Formol)FDA Link 01/2021 - 03/2004
3	AntiemeticsIBA 10/2020 - 01/2018
3	Monoclonal AntibodiesIBA 01/2020 - 10/2010
3	Anaplastic Lymphoma KinaseIBA 01/2019 - 11/2013
3	ezrinIBA 11/2017 - 07/2015
3	amrubicinIBA 01/2017 - 09/2010
3	Etoposide (VP 16)FDA LinkGeneric 08/2016 - 09/2003
3	Docosahexaenoic AcidsIBA 01/2011 - 03/2008
3	MicellesIBA 12/2010 - 07/2009
3	ATP-Binding Cassette Transporters (ABC Transporters)IBA 07/2009 - 03/2004
3	Polysorbates (PSML)FDA Link 07/2008 - 04/2002
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2021
2	atezolizumabIBA 07/2021 - 04/2021
2	ParaffinIBA 01/2021 - 12/2008
2	Programmed Cell Death 1 ReceptorIBA 01/2021 - 11/2020
2	NucleotidesIBA 01/2021 - 05/2018
2	B7-H1 AntigenIBA 01/2021 - 07/2020
2	Serine (L-Serine)FDA Link 01/2021 - 12/2018
2	LigandsIBA 11/2020 - 10/2019
2	Dexamethasone (Maxidex)FDA LinkGeneric 10/2020 - 01/2018

Therapy/Procedure

52	Drug Therapy (Chemotherapy) 04/2022 - 07/2003
36	Therapeutics 04/2022 - 03/2006
11	Radiotherapy 01/2020 - 03/2005
10	Chemoradiotherapy 01/2020 - 06/2008
7	Combination Drug Therapy (Combination Chemotherapy) 07/2019 - 07/2003
4	Precision Medicine 01/2022 - 07/2020
3	Palliative Care (Palliative Therapy) 04/2022 - 01/2017
3	Proton Therapy 01/2020 - 01/2016
3	Induction Chemotherapy 01/2017 - 03/2005
3	Aftercare (After-Treatment) 02/2015 - 07/2009
2	Immunotherapy 04/2021 - 01/2020
2	Surgical Instruments (Clip) 01/2021 - 07/2020
2	Lymph Node Excision (Lymph Node Dissection) 01/2021 - 07/2019